Question

The archaeon Sulfolobus acidocaldarius is found in hot acidic springs. Its genome encodes a gene for...

The archaeon Sulfolobus acidocaldarius is found in hot acidic springs. Its genome encodes a gene for an ATP-driven topoisomerase that introduces positive supercoils into its circular genome. Why is the presence of this gene so critical to Sulfolobus acidocaldarius?

Homework Answers

Answer #1

DNA is a temperature-sensitive molecule and will get denatured if exposed to high temperatures. the positive supercoiling is the form of DNA in which DNA is tightly packed is completely unaccessible. Since these bacteria are living in high temperature they need to pack the DNA tightly in order to prevent the heat-induced denaturation of DNA. If the DNA is negatively supercoiled or more opens there are the chances that it could be denatured by the heat. So in order to maintain the positive supercoiling, so the stability of DNA they use topoisomerase to induce positive supercoiling. If these genes for topoisomerase are absent the bacteria would not be able to pack the DNA tightly and it will remain more relaxed form which will increase the heat induced denaturtaion of DNA leading the death of bacteria.

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old...
READ THE CASE STUDY AND ANSWER THE FOLLOWING QUESTIONS 2nd CASE: An Unexplained Death A 65-year-old man of Scandinavian descent was rushed to the Emergency Room of your local hospital after a family member discovered him unconscious in his home. The woman who dialed “911” told the dispatcher that the man, her brother, was the local librarian of the past 10 years and had no spouse or children. She reported that they had spoken the day before, and he had...
Company Case Allstate: Bringing Mayhem to the Auto Insurance Advertising Wars In the spring of 1950,...
Company Case Allstate: Bringing Mayhem to the Auto Insurance Advertising Wars In the spring of 1950, the teenage daughter of Allstate general sales manager Davis Ellis was stricken with hepatitis shortly be- fore she was to graduate from high school. The worried executive arrived home from work one evening just as his wife returned from the hospital where their daughter was admitted. As he met her at the front door, his wife reported, “The hospital said not to worry. ....
Delta airlines case study Global strategy. Describe the current global strategy and provide evidence about how...
Delta airlines case study Global strategy. Describe the current global strategy and provide evidence about how the firms resources incompetencies support the given pressures regarding costs and local responsiveness. Describe entry modes have they usually used, and whether they are appropriate for the given strategy. Any key issues in their global strategy? casestudy: Atlanta, June 17, 2014. Sea of Delta employees and their families swarmed between food trucks, amusement park booths, and entertainment venues that were scattered throughout what would...