Question

Question 16 (1 point)

In the latex agglutination assay for rheumatoid factor, the antigen coated on the latex beads is

Question 16 options:

	IgG with the Fc facing in
	IgG with the Fc facing out
	CCP and IgG with the Fc facing out
	CCP

Question 17 (1 point)

Autoimmunity can be

Question 17 options:

	infection associated because of a cross-reactive epitope
	environmentally associated
	trauma associated
	all of these

Question 18 (1 point)

Which of the following is used for testing the specificity of the antibody in a patient suspected of having SLE?

Question 18 options:

	ANA testing on HEP-2 cells
	ELISA testing
	testing on Crithidia luciliae
	all of these

Question 19 (1 point)

Systemic lupus erythematosus (SLE) is associated with

Question 19 options:

	decreased clearance of dead and dying cells
	increased clearance of dead and dying cells
	high titers of rheumatoid factor
	excess complement concentrations

Question 20 (1 point)

Antibodies to cyclic citrullinated peptides (CCP)

Question 20 options:

	recognize antigens that contain an arginyl converted to a cyclic citrullyl
	have a high specificity for the diagnosis of rheumatoid arthritis
	have a high specificity for the diagnosis of SLE
	first and second responses

Answer 1

Q.16

IgG with Fc facing out on latex beads.

(antigen is coated on latex beads and IgG binds in such a way that Fc region remains out)

Q 17

All of the above.

Cross reactive epitope is main cause

environmemtal cause is also established

Emotional stress can also cause auto immune disorder as per new research done.

Q 18

All of the above

All above mentioned techniques used for SLE

Q 19

high titers of rhematoid factor

high complement associated with cancer, viral disease etc

Q 20

First and second response