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Identify betaine's overall potential epigenetic role- does it work on certain genes to turn them on...

Identify betaine's overall potential epigenetic role- does it work on certain genes to turn them on or off; which ones?

Feel free to elaborate and give a great answer but also explain in understandable terms. Thank you!

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Betaine is an amino acid found in many nutritional supplement has a potential role in epigenetics. Betaine along with other nutritional supplement and environmental conditions, changes the DNA methylation states by by providing a methyl group for the synthesis of adomet. Adomet is responsible for the methylation of DNA. Methylation of DNA changes the expression of a gene. Various research has shown the alteration of many gene expression by supplementation with betaine and many other nutrients like folate, vitamin B12 etc.

Supplementation of viable yellow agouti dams with a combination of folic acid, vitamin B12, choline and betaine increases CpG methylation at Avy locus in DNA altered the coat colour of the offspring, presumably by switching off expression of the agouti gene.

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