Question

Cystic fibrosis (CF) is an autosomal recessive disease. In a South American country, a study was conducted to test the hypothesis that cystic fibrosis carriers were less likely to be affected and die from by tuberculosis (TB) infection. To begin the quantitative study, researchers needed to identify the number of individuals in the population that were carriers, knowing the frequency of the cystic fibrosis allele was 0.1 in the population. After their analysis, the researchers concluded that there was evidence to support their hypothesis.

1. The researchers determined ___% of the population to be
cystic fibrosis carriers.

(round up and enter only a whole number with no commas, periods, or
other symbols)

Answer #1

Cystic fibrosis (CF) is an autosomal recessive disease. In a
South American country, a study was conducted to test the
hypothesis that cystic fibrosis carriers were less likely to be
affected and die from by tuberculosis (TB) infection. To begin the
quantitative study, researchers needed to identify the number of
individuals in the population that were carriers, knowing the
frequency of the cystic fibrosis allele was 0.1 in the population.
After their analysis, the researchers concluded that there was
evidence...

Among U.S. Caucasians, the frequency of the CF- allele causing
the recessive autosomal disease cystic fibrosis is 0.02. What is
the Δq for the CF allele after one generation of random
mating and selection?

Question 5
Cystic fibrosis (CF) is a recessive gene disease meaning that a
child has to inherit a defective CF gene from each parent. This
means that there is a 25% chance of a child having cystic fibrosis
if both parents are CF carriers Hence the number of children with
CF (in a family whose parents are CF carriers) has a binomial
distribution with n = the number of children in the family and p=
0.25
i. In a family...

Question 5
Cystic fibrosis (CF) is a recessive gene disease meaning that a
child has to inherit a defective CF gene from each parent. This
means that there is a 25% chance of a child having cystic fibrosis
if both parents are CF carriers Hence the number of children with
CF (in a family whose parents are CF carriers) has a binomial
distribution with n = the number of children in the family and p=
0.25
i. In a family...

The Autosomal Recessive disease, Cystic Fibrosis (CF),
runs in Jill’s family. Jill is unaffected. Based on this data,
select which of the following statements could be True?
A.
If Jill’s Paternal Aunt is affected and her Paternal
Grandparents are unaffected. There is a 2/3 probability her father
is a Carrier
B.
In the future, Jill’s parents have another child and
that child has CF. Therefore, her parents have a 100% probability
of being Carriers
C.
Jill could never produce a...

The Autosomal Recessive disease, Cystic Fibrosis (CF), runs in
Jill’s family. Jill is unaffected. Based on this data, select which
of the following statements could be True?
A.
If Jill’s Paternal Aunt is affected and her Paternal
Grandparents are unaffected. There is a 2/3 probability her father
is a Carrier
B.
In the future, Jill’s parents have another child and that child
has CF. Therefore, her parents have a 100% probability of being
Carriers
C.
Jill could never produce a...

Cystic fibrosis is one of the most common autosomal recessive
disorders. The carrier frequency in a general population is 1/25. A
woman who knows she is heterozygous for the mutation that causes
cystic fibrosis (CF) marries a man with no family history of CF at
all. What is the probability that they will produce a child that
has cystic fibrosis?
Suppose the couple above has a child with cystic fibrosis. What
is the chance that their second child will have...

Cystic fibrosis is one of the most common autosomal recessive
disorders. The carrier frequency in a general population is 1/25. A
woman who knows she is heterozygous for the mutation that causes
cystic fibrosis (CF) marries a man with no family history of CF at
all. What is the probability that they will produce a child that
has cystic fibrosis? Suppose the couple above has a child with
cystic fibrosis. What is the chance that their second child will
have...

Cystic fibrosis is an autosomal recessive disorder caused by a
loss-of-function mutation in a chlorine channel, which causes a
thickening of the mucus, leading to respiratory failure. This
disease affects approximately 1 in 1353 newborns in the Republic of
Ireland every year.
Fill in the following values:
p =
q =
Current population of Ireland is approximately 4.8
million. Based on the allele frequencies that you calculated, what
is the expected number of cystic fibrosis carriers (heterozygotes)
in Ireland? Show...

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