older individuals ‘vulnerability to diabetes and insulin resistance increase with age, and this is reflected by their chronically
- lower cortisol levels
- higher cortisol levels
Higher cortisol levels.
Cortisol is a glucocorticoid hormone, its secretion increased in stres, low glucose level in blood and in aged people. Cortisol hormone takes part in gluconeogenesis, and decrease the transport of glucose through transporters causing insulin resistance. Glycogenesis also enhanced by cortisol. These all promote accumulation of glucose and leading to tpe 2 diabetes. Due to this reason older individuals ‘show vulnerability to diabetes and insulin resistance with age.
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