How does DNA methylation in some eukaryotes get inherited in progeny?
DNA methylation occurs at the cytosine bases of eukaryotic DNA ,which are converted to 5-methylcystosine by DNA methyltransferase (DNMT) enzymes.The altered cytosine residues are usually immediately adjacent to guanine nucleotide ,resulting in two methylated cystozine residues sitting diagonally to each other on opposing DNA strands.Copying the methylation from existing DNA strand to its new partner after replication.Methylation plays crucial role in gene expression by blocking promotors at which activating transcription factors should blind.Proper DNA metylation is important for cell differenciation and embryonic development.It play role in gene expression also .Methylation near gene promotors varies depending on cell type,with more methylation of promotors correlating with low or no transcription.
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