Question

1. The ______ __________ allows for flexibility in the codon-anticodon interaction at the third position.
2. The ______________ ___________ are enzymes that link amino acids with their appropriate tRNAs.
3. The transfer of polypeptides into the ER is called _______________ ______ because the movement across the membrane is coupled with translation.

Answer 1

1) The answer will be wobble hypothesis.

Explanation: According to wobble hypothesis, codon-anticodon pairing at the first two bases of codon (From 5' end) strictly follow Watson-Crick base pairing. But third base of the codon (3' end) can undergo non-Watson-Crick base pairing with the first base of anticodon (5' end). As a result, there is some flexibility in the codon-anticodon interaction at the third position.

2) The answer will be aminoacyl-tRNA synthetases.

Explanation: Aminoacyl-tRNA synthetases are responsible for specificity for an amino acid & its tRNA. A cell contains 20 different aminoacyl-tRNA synthetases, one for each amino acid.

3) The answer will be co-translational import.

Explanation: Co-translational import is a process in which polypeptide synthesis (Translation) is concurrent with the transfer of polypeptides.