Prokaryotes | Eukaryotes |
Mostly unicellular | mostly multicellular |
Nucleus lacks nuclear membrane and nucleolus | nuclear membrane and the nucleolus are present. |
Chromosome is usually single circular without histone protein. | Chromosomes are multiple, linear with histone proteins |
Genes are expressed in groups called operons. |
Genes are expressed individually |
Mitochondria, chloroplast, endoplasmic reticulum, golgi complex, membrane bound vacuoles, lysosomes and peroxisomes are absent. | Mitochondria, chloroplast, endoplasmic reticulum, golgi complex, membrane bound vacuoles, lysosomes and peroxisomes are present. |
Similarities:
1. Both are made up of cells.
2. Both have cell membrane.
3. Both have ribosomes.
4. Both have cytoplasm.
5. Both have DNA and its central dogma which involves replication, transcription and translation.
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