Question

What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that...

What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that deficiency?

Homework Answers

Answer #1

Answer:

What is the clinical deficiency presented by hemophilic people?

  • Hemophilia is a mostly inherited genetic blood clotting disorder. There are two types of Hemophilia - A and B
  • Both Hemophilia A and B are X linked recessive heriditary disorders.
  • Hemophilia A is caused due to the defective or deficient factor VIII
  • Hemophilia B is caused due to deficiency of factor IX. In some cases, factor IX may be present, but it is non-functional.

What is the genetic cause of that deficiency?

  • ​Hemophilia A is caused due to a mutation in the gene that encodes coagulation factor VIII.
  • This gene is present on chromosome Xq28
  • ​Hemophilia B is caused due to a mutation in the gene that encodes coagulation factor IX.
  • This gene is present on chromosome Xq27.1
  • Since Hemophilia is X-linked disorder, therefore, it can be passed down only from mother.
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that...
What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that deficiency?
What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that...
What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that deficiency?
What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that...
What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that deficiency?
Compare and contract iron deficiency anemia with folate acid deficiency anemia including clinical manifestations of each...
Compare and contract iron deficiency anemia with folate acid deficiency anemia including clinical manifestations of each anemia
During clinical trials, fedratinib, a Janus Kinase inhibitor, was found to cause thiamine (Vitamin B1) deficiency...
During clinical trials, fedratinib, a Janus Kinase inhibitor, was found to cause thiamine (Vitamin B1) deficiency in a group of patients. Please indicate which of the following statements is most consistent with this observation? 1. Fedratinib inhibited the efflux pump, P-glycoprotein, which is localized to the apical membrane of the intestine. 2. Fedratinib inhibited the thiamine transporter, THTR2 (SLC19A3), found on the apical membrane of the intestine. 3. Fedratinib stimulated the thiamine transporter, THTR2 (SLC19A3), found on the apical membrane...
2. Describe the clinical significance of a Protein C or S deficiency in the coagulation cascade?
2. Describe the clinical significance of a Protein C or S deficiency in the coagulation cascade?
Human immuno deficiency virus (HIV) has a protein coat and a genetic material which is (a)...
Human immuno deficiency virus (HIV) has a protein coat and a genetic material which is (a) double stranded RNA (b) double stranded DNA (c) single stranded DNA (d) single stranded RNA.
People with a deficiency in the TAP, transporter for antigen processing, have partial immunodeficiency as well...
People with a deficiency in the TAP, transporter for antigen processing, have partial immunodeficiency as well as autoimmune manifestations. You see both immune deficiency and autoimmunity in people with this disorder, why?
There is a study that shows that people who are obese have a vitamin D deficiency....
There is a study that shows that people who are obese have a vitamin D deficiency. Does that mean that obesity causes a deficiency in vitamin D? Explain
Color blindness, or dyschromatopsia, is a form of genetic deficiency in color perception. The condition is...
Color blindness, or dyschromatopsia, is a form of genetic deficiency in color perception. The condition is much more prevalent among males than females, pointing to a genetic connection with the X chromosome. The frequency of dyschromatopsia in the Caucasian American male population is about 9%. However, it is thought that this proportion might be smaller among males of other ethnicities. We want to estimate the proportion of Asian American males who are color-blind. How large a sample size do we...