Question

In old exams, I asked students to link two concepts by a verb. For the following answers about DNA polymerase I and primers, which one does NOT follow the meaning of the textbook?

		DNA polymerase I removes primers
		DNA polymerase I synthesizes primers
		DNA polymerase I extends primers
		DNA polymerase I adds nucleotide to the primer

Answer 1

Answer .

DNA polymerase I synthesizes primers

Primers are synthesized by primase enzyme which is not a DNA polymerase but RNA polymerase. Primers are short strech of bases complementary to the template DNA. DNA polymerase I can extends DNA in 5'- 3' direction. So, Primers provides free 3' OH end to DNA polymerase I to add nucleotides. Also DNA pol I can also remove RNA primers and replace with DNA fragments in okazaki fragments. Pol I can also repair damaged DNA.

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