Question

In Eukaryotic genes, which of the following is the regulatory region?

	A.	Poly A tail
	B.	Transcription factors
	C.	Exons
	D.	Promoter
	E.	5' Cap
	F.	Introns

Answer 1

The correct option is D. Promoter.

Gene promoters are present on the upstream of the gene and have regulatory elements away from the transcriptional initiation site. The transcriptional complex causes the DNA to bend back on itself, which permits for placement of regulatory sequences far from the original site of transcription in eukaryotes. Eukaryotic promoter regulatory sequences bind proteins known as transcription factors, which are involved in the formation of the transcriptional complex. Promoters represent critical elements, which function in concert with other regulatory regions such as enhancers, silencers, boundary elements to direct the level of transcription of a gene. A promoter is induced in response to modifies in abundance and conformation of regulatory proteins in a cell, which enable in activation of transcription factors to recruit RNA polymerase.