True or False?
Lck phosphorylated tyrosine residues within the cytoplasmic tail of the t cell receptor to activate naive T cells.
Lck phosphorylated tyrosine residues within the cytoplasmic tail of the t cell receptor to activate native T cells.
Answer: True
Explanation:
Lck belongs to Src family of protein tyrosine kinases (PTKs). T
cells originate in the bone marrow and its maturation takes place
in
thymus where it differentiated to form memory T cells. Lck in T
cells serves as a signalling
molecule by phosphorylating the tyrosine residue of T cell receptor
in activation of T cells.
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