Question

What must be added to the template strand before DNA polymerase can begin synthesis of a...

What must be added to the template strand before DNA polymerase can begin synthesis of a new DNA strand?

Homework Answers

Answer #1

DNA polymerase is an enzyme that plays a key role in the replication of DNA. DNA polymerases can add nucleotides complementary to the template strand and that happens in a particular direction i.e to the 3' end of the new DNA strand. So, the dNTPs are one of the pre-requisites. Moreover, a primer of a few nucleotides in length is also required which would be complementary to a part of the template strand. A typical primer length varies from 5-10 nucleotides. Once, the primer is in place, the DNA polymerase can keep adding the dNTPs to the 3' end and keep synthesizing DNA from 5' to 3' end.

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