Question

A researcher is interested in a novel gene in drosophila called “COVID” which causes the flies...

A researcher is interested in a novel gene in drosophila called “COVID” which causes the flies to become antisocial and maintain a large distance from other flies. She performs two “reciprocal crosses” to determine the possible genetics of this gene. First, she crosses a true-breeding COVID female to a true-breeding wild-type male and produces the following progeny: All of the female progeny are wild-type and all of the male progeny from this cross are COVID. Next, she does a reciprocal cross and mates a true-breeding male COVID fly to a true-breeding female wild-type and generates the following progeny: All flies are wild-type. What is a possible explanation for our researcher’s results?

Group of answer choices

COVID is autosomal recessive.

COVID is sex-linked dominant.

COVID is autosomal dominant with incomplete penetrance.

COVID is sex-linked recessive.

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Answer #1

d) COVID is sex-linked recessive.

let the alleles be Xc- COVID phenotype, XC- normal flies

genotype of the true breeding COVID females is XcXc and genotype of normal males is XCY

XCY * XcXc

XC Y
Xc XCXc ( wildtype female) XcY ( COVID male)
Xc XCXc ( wildtype female) XcY ( COVID male)

all female progenies are wildtype and all males shows COVID phenotype.

Now let`s do reciprocal cross

wildtype female * COVID male

XCXC * XcY

XC XC
Xc XCXc ( normal female) XCXc ( normal female)
Y XCY ( normal male) XCY ( normal male)

all progenies are normal.

so the mode of inheritance of COVID is Sex-linked recessive.

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