Question

Consider this hypothetical situation: you are heterozygous for an autosomal recessive genetic disorder and your potential reproductive partner is also heterozygous for that same recessive genetic disorder.

a. Do you and your potential partner exhibit the recessive phenotype?

b. What is the probability the offspring of this breeding pair will have the recessive phenotype?

c. Would you have children with this person? Why or why not?

d. Should people known to be carriers of a recessive genetic disorder be legally prohibited from having children? Why or why not?

Answer 1

Answer:

a). No, both the paents would not express the recessive phenotype due to heterozygoys condition. Recessive phenotype is appeared when both the recessive alleles are present in an individual

b).

Aa x Aa ---Parents

	A	a
A	AA (normal)	Aa (normal)
A	Aa (normal)	aa (recessive disease)

Normal = ¾

Recessive disease = ¼

The probability the offspring of this breeding pair will have the recessive phenotype = 1/4

c). Yes, we have children of both normal and recessive disorder with ¾ & ¼ proportions respectively. The children would be alive as the disease is not lethal.

d). If both the parents ae heterozygous, 25% of their children will get the disorder. Based on this, we can legally prohibit to get marry instead of prohibiting children. Because, no couple accept to have children once married