Question

True or false: Glucose, glycerol, and free fatty acids all require the use of the electron transport chain and oxidative phosphorylation to produce ATP.

Answer 1

False

ATP is produced by substrate level phosphorylation and oxidative phosphorylation. 2 net ATP molecules are produced by glycolysis of one molecule of glucose, by substrate level phosphorylation. Rest of the energy of oxidation is stored in reducing powers like NADH and FADH which goes to mitochondrial ETC (electron transport chain ) to give electron for oxidative phosphorylation to produce ATP. This is why cells like RBCs which lack mitochondria and cannot perform oxidative phosphorylation can obtain energy by glycolysis. substrate level phosphorylation will produce less ATP molecules compared to oxidative phosphorylation.