A genetic mutation results in cells containing mitochondria with unfolded cristae. What generalizations can you make about this persons metabolism?
A genetic mutation in the mitochondrial DNA leading to the formation of unfolded cristae would reduce the ability of the powerhouse of the cell to generate energy and slows down metabolism with severe to mild effect in individuals. The area surrounding the cristae houses the enzymes needed for the citric acid cycle to metabolize carbohydrate and fatty acid regulation. Cristae increase the surface area inside the mitochondria where the ETC occurs thereby reducing the ability of the mitochondria to supply ATP. The person is likely to become lethargic, metabolism will slow down and will show greater tendency to become fatty easily.
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