Question

Developmental biology

1. Protein dsh is transported towards the dorsal side of the frog embryo by the following protein

a) GBP

b) Wnt

c) Hh

d) Dpp

2. Each cell division in mammals during early embryogenesis takes approximately

a) 8 minutes

b) 1 hour

c) 5 hour

d) more than 10 hour

3. One protein has been found to stimulate limb regeneration in newts

a) Hh

b) Dpp

c) nAG

d) none of the above

4. Embryonic epiblast contributes to the formation of

a) embryonic ectoderm

b) ammionif ectoderm

c) Yolk sac

d) none of the above

5. The immediate recipient of the hippo signal in the mouse blastocyst is

a) Yap

b) Lats

c) Tead4

d) Cdx2

6. one protein that is not regulated by beta-catenin

a) siamois

b) twin

c) chordin

d) none of the above

Answer 1

1.) b, wnt, Wnt pathway is the one regulating the formation of dorsal ventral axis in frog. It stimulates the formation of dorsal axis.

2.) d, more than 10 hrs, to be specific it takes approximately 12-24 hrs for the cell to divide everytim .

3.) c, nAG, nAG is the protein that helps in regeneration of the limbs in newt.

4.) b, amniotic ectoderm, Amniotic ectoderm is the lining of amniotic cavity formed from embryonic epiblast.

5.) b, Lats, the pathway starts with activation of Lats which transfer signal to yap.

6.) b, twin protein, it is not regulated by beta catenin whereas others are regulated.