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What percentage of carbon atoms in cholesterol are derived from acetyl-coA?

What percentage of carbon atoms in cholesterol are derived from acetyl-coA?

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All 27 carbon atoms of cholesterol are derived from avetyl-coA. Biosynthesis of cholesterol generally takes place in the Endoplasmic reticulum of hepatic cells and begins with acetyl coA which is derived from an oxidation reduction reaction in the mitochondria.

Cholesterol synthesis takes place in all cell types. However the liver represent the main site for de novo cholesterol synthesis contributing to approximately 80% of total cholesterol synthesis in mammals. Cholesterol is generated from acetyl coA via a complex multistep process.

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