Question

What is the proposed relationship between the number of TRAP subunits and the number of TRAP binding targets on the RNA transcript?

Answer 1

Answer :

The trp RNA binding Attenuation Protein TRAP regulates expression of the tryptophan biosynthetic and transport genes in bacillus subtilis in response to changes in the level of intracellular tryptophan.

TRAP binding promote formation of a transcription termination structure, that halts transcription prior to structural genes.

TRAP consists of 11 identical subunits and is activated to bind RNA by binding 11 molecules of tryptophan. The TRAP binding site in leader region of trp operon mRNA consists of 11(G/U) AG repeats. Tis is the proposed model of 11 TRAP subunits and binding targets.