Question

If you take a random sampling of 100,000 human beings and find that only 1 of them has substituted an A at a location where the other 99,999 have a T, this would be considered a

Base pair substitution

Point mutation

SNP, a Single nucleotide polymorphism

Translocation

Answer 1

It would be cosidered as a SNP, a Single Nucleotide polymorphism. It is also a case of base transition (i.e. point mutation) which depicts the interchange of a purine (A,G) with a pyrimidine (T,C) in a DNA strand and vice versa. Here T is replaced by a A but this scenario is about 100000 people. So here most f the genome has T at a particular position but only one has A on that place which is only a single nucleotide change. So it is a single nucleotide polymorphism.

It can't be base pair substitution as because here base pair has not been substituted and on the other hand it can't be translocation because no segment of gene is here translocated.