Question

Explain Hyposegmented

Answer 1

Answer :-

Hyposegmented:

It is also known as hypolobulated .

It is term given to abnormal neutrophils having few lobes i.e less than three lobes.

Normally neutrophils have more than three lobes.

Causes :- it may be acquired phenomenon due to burns , severe enjury , malignancy,severe infections,and drugs like sulphonamides

It may causes due to mutations in LBR gene which results in hyposegmented neutrophils along with mild skeletal symptoms.

Diagnosis :- it can be diagnosed by blood smear test.