Question

As part of a cancer research project, you have discovered a gene that is mutated in many metastatic tumors. After determining the DNA sequence of this gene, you compare the sequence with those of other genes in the human genome sequence database. Your gene appears to code for an amino acid sequence that resembles sequences found in some serine proteases. Conjecture how your new gene might contribute to the development of highly invasive cancers.

Answer 1

In the above Question:

· The   discovered gene which is mutated in many metastatic tumors, its sequence resembles serine proteases, As we know In cancer, Serine proteases (or serine endopeptidases) mediate a variety of events relevant to fundamental processes of tumor invasion and metastasis

· Like in ovarian cancer, they are known for growth and spread of tumor and thus if their production is detected early in a way we can be detect formation of tumour.

· Thus a link between serine protease functions and cancer outcomes suggests that this gene might be a suitable target as a tumor biomarker, as detecting its levels hold promise as a means of identifying certain cancers at an early stage to guide treatment