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Prokaryotic polypeptides that end in the amino acid sequence ANDENYALAA will be destroyed. Where does the...

Prokaryotic polypeptides that end in the amino acid sequence ANDENYALAA will be destroyed. Where does the information for this sequence originate?

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It is encoded within the gene that codes for that polypeptide.

It is attached by the Ski7 protein when it recognizes that the protein is misfolding.

It is added by a suppressor tRNA.

It is encoded by the tmRNA molecule.

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Answer #1

Answer is D.

tmRNA stands for transfer-messenger RNA. It is the complex which is formed by the transfer RNA, messenger RNA, some ribonucleoprotein, elongation factor and ribosomal protein. It is found in prokaryotes. It has the special properties of adding tag to the protein. It tags the amino acid sequence ANDENYALAA at thr end of protein. The ANDENYALAA coding sequence is found in mRNA. The transfer RNA carries amino acid and ribosomes provides the environment. Hence if this tag is destroyed, then the information for this sequence will originate in tmRNA molecule.

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