Question

9. A new anti-viral treatment called Whibluedesvir has recently been touted in the media as being highly effective. Two studies followed up on the treatment (see below). Which study are you more likely to believe, and why? (6 pts)

Study 1: compared a single high dose of Whibluedesvir to a single low dose of Whibluedesvir and an untreated group; 5 patients in each group; quantify levels of virus in patients 2 days after treatment; report a p-value of 0.001 when they compare the high dose to the untreated group.

Study 2: compared 5 different treatment concentrations (each administered twice) to an untreated group; minimum of 45 patients in each group; quantify levels of virus in patients 2 days after the last treatment; report p-values of 0.89, 0.27, 0.56, 0.78, and 0.12 when compared to the untreated group.

Answer #1

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