For human blood, there are two alleles (called R and r) and the frequencies of these alleles in a population of 1000 individuals were 0.3 for R and 0.7 for r. What is the expected frequencies and number of individuals with the genotypes RR, Rr and rr?
Answer.
Allelic frequency is calculated as=Number of individuals of R(X) /total number of individuals
So, here we need to calculate X= 1000X0.3=300 individuals
For small r,
X=0.7X1000=700 individuals
R=300 individuals and r=700 individuals
RR= 0.3X0.3= 0.09
Rr= 0.3X0.7= 0.21
rr= 0.7X0.7=0.49
If the population is in HW equilibrium, then
p=dominant allele and q is the recessive allele
p^2+2pq+q^2=1
0.09+2X0.21+0.49=1
Means,the population is in HW equilibrium.
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