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Discuss the reason why elimination of maternal mRNA and eventually, many maternally inherited proteins is essential...

Discuss the reason why elimination of maternal mRNA and eventually, many maternally inherited proteins is essential for normal and what are they largely replaced with when the embryonic genome becomes fully active?

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Elimination of maternal mRNA and maternally inherited proteins is essential for normal because it is the stage in embryonic development during which development comes under the exclusive control of the zygotic genome rather than the maternal (egg) genome. It is also known as Embryonic Genome Activation or Maternal to zygotic transition (MZT).

This is essential because this maternal mRNA controls embryo development until the onset of Embryonic Genome Activation.

This process is important because fromnnow onwards the new embryonic genome is expressed and the paternal and maternal genomes are now used in combination which means different alleles will be expressed.

When the embryonic genome becomes fully active these maternal mRNA are degraded and are replaced by zygotic transcripts which changes pattern of gene expression, to novel embryo-specific transcripts.

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