Question

A woman in Scotland can feel virtually no pain due to a mutation in an unidentified gene- when a research team of geneticists at UCL in London studied Jo Cameron, they discovered the following:
   a.    They found higher levels of expression of genes that suppress inflammation.
   b.    They found lower levels of canabinnoids that regulate pain sensation and memory.
   c.    They found mutations in three separate genes that code for pain receptors.
   d.    They found aA new mutation that is a deletion of a segment of a previously unknown gene.

Answer 1

Ans: According to James Cox "We found this woman has a particular genotype that reduces activity of a gene already considered to be a possible target for pain and anxiety treatments," Also scientists discovered that two mutations could be responsible for her condition—one of which, known as FAAH-OUT, has been described for the first time.

FAAH is a protein that breaks down anandamide, also known as the “bliss molecule,” which is a neurotransmitter that binds to cannabinoid receptors. These are some of the same receptors that are activated by marijuana. With FAAH-OUT mutation the patient has less FAAH activity and the patient was found to have more circulating levels of anandamide, which may explain her resistance to feeling pain.

So from all this we can conclude that they found lower levels of canabinnoids that regulate pain sensation and memory. So option b is correct