Question

Why is eukaryotic DNA underwound, even though eukaryotes lack topoisomerases that can introduce supercoils?

Why is eukaryotic DNA underwound, even though eukaryotes lack topoisomerases that can introduce supercoils?

Science   Biology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Eukaryotic DNA is underwound or negatively supercoiled because
Supercoils in eukaryotes are generated by DNA-binding proteins as a result of transcribing or replicating a segment of DNA, bending, and these are then introduced by nucleosome core particles, DNA helicases and polymerases. Like when a RNA polymerase transcribes a region of chromatin , we never find it rotating with tight helical part of DNA thus, generating overwound DNA ahead of it and underwound DNA nehind it so here transcription plays a key role in generation of DNA negative supercoils. These supercoils are on surface of histone proteins, and this supercoil is released when nuceleosome disassemble or DNA is unwrapped.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Why do members of phyla such as Porifera and Platyhelminthes lack gills, even though they live...
Why do members of phyla such as Porifera and Platyhelminthes lack gills, even though they live in aquatic environments?
What is/are the main difference(s) between prokaryotic and eukaryotic transcription regulation? a. chromatin structure in eukaryotic...
What is/are the main difference(s) between prokaryotic and eukaryotic transcription regulation? a. chromatin structure in eukaryotic DNA b. compartmentalized transcription and translation in eukaryotes c. lack of repressor elements in eukaryotic DNA d. a and b e. a, b, and c
What is a major difference between eukaryotic DNA replication and prokaryotic DNA replication? a. DNA pol...
What is a major difference between eukaryotic DNA replication and prokaryotic DNA replication? a. DNA pol III of eukaryotes has both exonuclease activities while prokaryotic DNA pol III does not. b. There are many more types of prokaryotic DNA polymerases. c. Prokaryotic replication does not require a primer. d. Prokaryotic chromosomes are circular and so have no telomeres; eukaryotic chromosomes have telomeric replication.
Eukaryotic genes can be introduced into bacteria by recombinant DNA techniques. If the introduced gene encodes...
Eukaryotic genes can be introduced into bacteria by recombinant DNA techniques. If the introduced gene encodes a protein that is also found in bacteria - for example, a universally used glycolysis enzyme - then, expression of the eukaryotic gene may produce a protein that functions in the bacterial cell. The mouse gene for a glycolysis enzyme is introduced into an E. coli cell that has a mutant gene for the bacterial version of the same enzyme. Even though the mouse...
Eukaryotic genes can be introduced into bacteria by recombinant DNA techniques. If the introduced gene encodes...
Eukaryotic genes can be introduced into bacteria by recombinant DNA techniques. If the introduced gene encodes a protein that is also found in bacteria—for example, a universally used glycolysis enzyme—then, expression of the eukaryotic gene may produce a protein that functions in the bacterial cell. The mouse gene for a glycolysis enzyme is introduced into an E. coli cell that has a mutant gene for the bacterial version of the same enzyme. Even though the mouse enzyme should function in...
Compare and contrast the INITIATION of DNA replication in bacteria and eukaryotic cells. Which of the...
Compare and contrast the INITIATION of DNA replication in bacteria and eukaryotic cells. Which of the following is a correct statement of what the two processes have in common? explain the answer for each statement. 1. Both prokaryotes and eukaryotes regulate the start of DNA replication through methylation of the chromosomal DNA. 2. Both prokaryotes and eukaryotes tend to use multiple origins of replication in a chromosome. 3. DNA replication in both prokaryotes and eukaryotes initiates at regions of DNA...
Does eukaryotic DNA polymerase require a separate primase? Why or why not?
Does eukaryotic DNA polymerase require a separate primase? Why or why not?
Why are credit cards not included in the money supply even though they can be used...
Why are credit cards not included in the money supply even though they can be used easily for transactions? (Hint: What do you think happens when you use a credit card to purchase an item at a store?)
1. How does DNA methylation in some eukaryotes get inherited in progeny? 2. Why do disruptive...
1. How does DNA methylation in some eukaryotes get inherited in progeny? 2. Why do disruptive DNA lesions, like deletions and insertions, sometimes not lead to frameshift mutation?
Which of the following statements is incorrect about DNA replication? -The ends of eukaryotic chromosomes are...
Which of the following statements is incorrect about DNA replication? -The ends of eukaryotic chromosomes are replicated using single stranded DNA repeats and DNA polymerase -Post-replication mismatch repair is one mechanism that enhances the accuracy of DNA replication. -DNA replication is semi-conservative such that each daughter chromosome contains a single strand of DNA from the parental cell. -DNA replication is regulated so that it occurs only once during the cell cycle, in most eukaryotic cells. -Eukaryotic chromosomes tend to have...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT