Question

In one or two clear and concise sentences, explain why insulin is required for adipocytes to synthesize triacyl-glycerols from fatty acids.

Answer 1

            The actions of insulin to stimulate the synthesis of triacylglycerol in adipocytes can be diveded into categories based on time frame oof their stimulatort effects. Insulin signalling enhances lipid storage in adipocytes by both stimulating triacylglycerol synthesis and inhibiting it's breakdown.

               In adipocytes the stimulation of glucose entry acts in concert with the process of glyceroneogenesis,to provide intercellular substrate for synthesis of glycerol-3-phosphate needed for esterification of fatty acids into triacylglycerol.