Question

Case-2:

Complaint:

Five children from the same school presented with abdominal pain and diarrhea (streaked with blood) over a period of 3 days. Upon investigation it was found that those children had recently been in birthday party. Fecal specimen was collected and sent to microbiology lab. Lab report showed presence of pus cells on direct microscopy and non motile bacteria on motility test.

Clinical History: The children are usually healthy. They take no regular medications

a. What is the possible clinical diagnosis? bacillary dysentery.

b. What is the etiological agent and its natural reservoir?

causative agent is Shigella

Human are the natural reservoir

c. How could these infected children be treated?

d. Identify parasitic organism could resemble the same clinical feature of this infection and what laboratory test is used to diagnose it?

e. Identify a virus cause diarrhea with possibility of developing flaccid paralysis? What are the best samples for diagnosis of this virus? What immunological test can be used to confirm this viral infection? Is any prophylaxis available for this virus? If so, explain!

note : I only need to answer( c , d, e) questions

Answer 1

Answer-C The children can be treated by administration of oral rehydration therapy Alongwith of antibiotics combination. The antibiotics combination will kill the bacteria and will be effective even if the bacteria is resistant to some specific drug.

Answer-D The parasite may be E.coli or amoeba. These can be causative agent of dysentery. This can be detected by culturing.

Answer-E the virus that can cause flaccid paralysis is enterovirus. It can be detected by using ELISA with the blood as a sample.