mutation in a gene that encodes a protein engaged in quaternary structure will generally be classified as _________.
Answer. Point mutation.
Haemoglobin possess a tertiary structure because of its 4 polypeptides. A normal quaternary structure of haemoglobin gives RBC biconcave shape.
However, when a single mutation in DNA changes GAG to GTG, changes the hydrophilic amino acid glutamic acid to the hydrophobic valine.
As the a single base A is changed to T, thus this mutation is called a point mutation.
This disrupts the normal structure of haemoglobin and which makes RBCs sickle shaped.
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