Multiple choice questions ( questions may have more than one
answer )
1. Which of the following is true for tumor suppressor
protein?
a. A protein which gives a cell a growth advantage
b. A protein which inhibits cell proliferation
c. A protein which helps mitosis
d. Both alleles have to be inactivated to start
carcinogenesis
2. Which of the following statements about forensic analysis
of DNA is true?
a. A DNA profile using short tandem repeats (microsatellites)
is unique to an individual
b. Forensic analysis makes use of mutations in coding sequnces
to distinguish between individuals
c. PCR is used for DNA profiling (DNA fingerprinting)
d. DNA fingerprinting cannot be used for paternity
testing
3. what would be the effect on the primary structure of the
coded protein of a single base was deleted from a messenger RNA
transcript?
a. No effect
b. A single amino acid residue is changed
c. A complete change in amino acid sequence from the point
deletion, frameshift
d. In frame mutation
4-Mosaicisms:
a. All cells have the same karyotype
b. Some cells of the same patient have another karyotype
c. Can be seen in Down Syndrome
d. Occurs during G1-phase