What human tissues are affected by malaria? What are the main clinical manifestations of the disease?
Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoan.
(Plasmodium) P. falciparum P. vivax, P. ovale, and P. malariae causes malaria
Red blood cells and liver are mainly affected by malaria.
When you're bitten by a malaria-infected mosquito, the parasites that cause malaria are released into your blood and infect your liver cells. The parasite reproduces in the liver cells, which then burst open. This allows thousands of new parasites to enter the bloodstream and infect red blood cells.
Clinical manifestation include
Pain areas: in the abdomen or muscles
Whole body: chills, fatigue, fever, night sweats, shivering, or sweating
Gastrointestinal: diarrhoea, nausea, or vomiting
Also common: fast heart rate, headache, mental confusion, or pallor
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