Question

If you were interested in studying how brain regions communicate with each other during a particular activity, you might first use __________ to look at whole-brain activation and identify a brain region of interest. Then, if you wanted to identify where neurons in that brain region are sending signals to, you could use __________.

Group of answer choices

Immunohistochemistry; antisense oligonucleotides

Transcranial Magnetic Stimulation (TMS); microelectrodes

Functional Magnetic Resonance Imaging (fMRI); anterograde tracing with fluorescent microscopy

Structural Magnetic Resonance Imaging (sMRI); retrograde tracing with fluorescent microscopy

Answer 1

Functional magnetic resonance imaging, FMRI, is a technique which works by detecting the changes in blood oxygenation and flow that occur in response to neural activity. This is because when a brain area is more active it consumes more oxygen and to meet this increased demand blood flow increases to the active area. Anterograde tracing is a method which is used to trace axonal projections from their source (the cell body or soma) to their point of termination (the synapse).

Thus the correct is-

C- Functional Magnetic Resonance Imaging (fMRI); anterograde tracing with fluorescent microscopy