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population response to the coronavirus (children vs. adult vs. elderly) - how would a clinical trial...

population response to the coronavirus (children vs. adult vs. elderly) - how would a clinical trial be affected if enrolling adults vs,how the generalizability of the findings be applicable?

please I need answer in 6 lines with reference

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Answer #1

A test sample is a typical or ideal case that are ment to represents the population on average. But not always the study sample is representative of the population or we can say it can't be the exact generalization of the whole population. In case of corona virus the senario is different from the large animal sampling. Because as this virus undergoes rapid replication that cause mutation in the virus. The strain of the virus which may present in a personA may not be same in case for the personB.  So in case of clinical trial for coron virus sampling between few sample human will not represent the generalized view of the population.

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