Question

Describe the link between protein structure/function, silent mutations, and the conservative nature of the genetic code. Your answer should contain a definition of silent mutation and an explanation for how the genetic code is conservative.

Answer 1

Solution-

• Silent mutations are mutations in DNA that do not have an observable effect on the organism's phenotype. They are a specific type of neutral mutation.
• because silent mutation is not considered for lethal because it is a change third codon of mRNA due to change at nucleotide at DNA level.
• due to wobble base pairing in codon anticodon binding, the third codon is not considered so only 1st and 2nd base of codon is considered perfectly to match with anticodons 2nd and 3rd base.
• So codons 3rd and anticodons first has some flexibilty over there.
• Many time multiple codon codes for single amino acids this is conservation nature of codon which is used in wobble base pairing.
• So different codon has single type of anticodon due to single type of aminoacylated tRNA.