Question

Determine whether the following statement is true or false and then explain why in one or two sentences

All 2^nd- messengers are H₂O-soluble and can diffuse freely through the solution of the cytosol.

Answer 1

Ans.False

All  2nd- messengers are H2O-soluble and can diffuse freely through the solution of the cytosol.

There are three basic types of secondary messenger molecules:

• Hydrophobic molecules: water-insoluble molecules such as diacylglycerol(DAG)and phosphatidylinositols, which are membrane-associated and diffuse from the plasma membrane into the intermembrane space where they can reach and regulate membrane-associated effector proteins
• Hydrophilic molecules: water-soluble molecules, such as cAMP, cGMP, IP3, and Ca2+, that are located within the cytosol
• Gases: nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H2S) which can diffuse both through cytosol and across cellular membranes.