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what needs to happen in the stomach and the small intestine for the digestive enzymes to...

what needs to happen in the stomach and the small intestine for the digestive enzymes to get activated
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In stomach, gastric juice release by gastric gland. Gastric juice have mainly HCL and digestive proenzyme like pepsinogen and prorennin (at infant stage). Pepsinogen and prorennin activated by HCL in to pepsin and rennin.

In small intestine, intestinal gland or crypts of Lieberkuhen secrete sucus entericus which has various type of digestive enzymes and a non digestive enzymes enterokinase. Enterokinase activate pancreatic proenzyme like chymotrypsinogen, trypsinogen and procarboxypeptidase respectively in to chymotrypsin, trypsin and carboxypeptidase. These enzyme also shows Autocatalytic activity.

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