Question

Tyrosine kinases catalyze chemical transformations of tyrosine amino acid residues. What is the typical nucleotide cofactor used by the kinase to perform this reaction? Draw the tyrosine structure before and after this reaction, showing proper stereochemistry. Which family of enzymes restores the original tyrosine structure?

Answer 1

Tyrosine kinase is an enzyme catalyses the transfer of phosphate group from ATP (nucleotide) to tyrosine amino acid present in protein. it acts as switch on or off for the function of protein and cellular function. this enzyme belongs to kinase enzyme family, which are involved in the transfer of phophate group (phosphorylation.

the phosphorylation by tyrosine kinase switch on the function and protein phosphatase enzyme working in reverse order, dephosphorylates the protein (tyrosine) to switch off the protein function.