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Drug-resistant TB can be acquired via sequential mutations in the pathogen’s genome, or via the transmission...

Drug-resistant TB can be acquired via sequential mutations in the pathogen’s genome, or via the transmission of a resistant pathogen from another person. How can these events be distinguished? Why is it important to know which is more prevalent?

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Nowadays Tuberculosis is a multidrug resistance disease which is a result of different types of drugs implemented on the pathogen. These drugs were given in a different manner so that the bacteria took some time to adapt in the presence of drugs and become mutated at the different sequences in the genome to increase the livingness of itself. However, on the other side, it infects another person via airways contact. Both of these are distinguished on the basis of their rate of transmission and effect on the body. More prevalent is the first one in which bacteria get resistant to the multi drugs thus a separate DOTS is given for six months.

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