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A drug holds complementary nitrogen bases with such strengths that the DNA is permanently fused in...

A drug holds complementary nitrogen bases with such strengths that the DNA is permanently fused in the shape of the double helix. Predict whether or not this drug might prove harmful. Provide at least two reasons why you think it may (or may not) be harmful.

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Answer #1

Drug may be harmful to DNA.

If the drug induce permanent shape of the double helix, it will effect replication and transcription process.

DNA unwinding or separation of double helix is necessary for DNA synthesis or DNA replication before cell division. Without unwinding of DNA strands, transcription will not proceed to form RNA from DNA. The RNA translated to protein for serving various functions in the cell, and thereby contributes the phenotypic expression. If the drug allow the DNA permanently to remain in it's double helix structure, unwinding of DNA will complicated and thereby affect cell division, and transcription.

Thus, the drug may effect cell machinery and functions by disrupting DNA unwinding processes.

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