Question

Apoptosis occurs when the tumor suppressor gene p53 is activated there is too much DNA damage...

Apoptosis occurs when

the tumor suppressor gene p53 is activated

there is too much DNA damage for the cell to repair

after the cell cycle has been arrested or stopped

all of the above

Homework Answers

Answer #1

Cell death is Apoptosis.The signal for cell death may come from the cell itself or from neighbouring cells.When the cell is in stress due to DNA repair...or cell cycle is stopped in cell cycle check points...In any case if the cell has not the ability to handle the corrections the only way is Apoptosis.This programmed cell death needs energy.But if cell is not going to Apoptosis pathway ,that cell may progress to tumors later. whenever cell has a problem related to check points p53 activated. Disruption of p53 leads to check point defects and later genomic instability

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