1) When faced with antibiotics the bacteria die , except those mutant bacteria in which a resistance is already present against the antibiotic. Slowely the number and the aggressiveness of such bacteria and there resistance to them increases . Actually due to natural selection, those bacteria are selected again and again which are best to survive against the antibiotics.
2) Multidrugs should be given to the bacteria at the same time. So, that the bacteria are not able to survive. Some bacteria which may have resusteance against some antibiotic will not have resistance against the others. And thus, they can be killed more efficiently. Thus it decreases the chances of getting a resistant bacteria to many folds.
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