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How can a diploid cell become triploid? I mean, I know that the process involves an...

How can a diploid cell become triploid? I mean, I know that the process involves an error during mitosis, but what kind of error? Can you provide some examples?

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A diploid cell becomes triploid usually during mitosis. It is often occurred in cancer cells where cell division process is not controlled. In cancer cells, mutation or over-expression of centrosomal protein "pericentrin" encoding gene leads to multipolar spindle formation rather bipolar fashion. As a consequence, chances of aneuploidy( 3N) increases due to non-disjunction (non-segregation) of sister chromatids. This leads to multipolar segregation of diploid chromosome into triploid chromosome.

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