Question

b) How does vitamin A normally affect the keratinocytes in the skin? Which form of vitamin A is involved in this?

Answer 1

Answer: Vitamin A(Retinoid) is an anti-keratinizing agent. Retinoids (RA) is a group of natural and synthetic Vitamin A. It plays a key role in the growth and differentiation of different cells in vivo and in vitro. Retinol stimulates the production of new cells in the skin.

The epidermis is one of the major targets for the retinoic acid. Keratinocytes constitute 90% of the cell of the epidermis the outermost layer of skin.it is a barrier of damage against heat, UV radiation, water loss, pathogenic bacteria, and fungi.

Retinol preform of Vitamin A is involved in Keratinocytes.It is biological active form of Vitamin A.