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Is the idiotype of a B cell lymphoma a tumor specific tumor antigen or tumor associated...

Is the idiotype of a B cell lymphoma a tumor specific tumor antigen or tumor associated tumor antigen?

A.

Tumor associated.
B.

Tumor specific.
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Answer #1

Answer: A. Tumor-specific

The idiotype of a B cell lymphoma is a tumor-specific. The idiotype is the commonly used tumor antigen in cancer vaccination. The idiotype is considered is a unique amino acid sequence of the heavy and light chain of immunoglobulin expressed on the surface of B-cell malignancies.

The ID of tumor immunoglobulin is different from the immunoglobulin expressed on the surface of a normal B cell. Therefore it is considered as tumor-specific antigen.

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