Question

I need to find information about CCR5 ( Cysteine-cysteine chemokine type 5 receptor) like active site, domains, motifs etc. and visualize those structures in PyMol. If you can't do the visualization please provide me with the information.

Protein primary structure is:

>NP_001092.1 actin, cytoplasmic 1 [Homo sapiens]
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYP
IEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVL
SLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVR
DIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFN
SIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLS
TFQQMWISKQEYDESGPSIVHRKCF

Answer 1

Ans:

The active site, domain and motif information for the amino acid sequence given above is provided as follows;

Domain information can be obtained by uploading given amino acid sequence in CDD (Conserved Domain Database)

Domain: NBD_sugar_kinase_HSP70_actin superfamily

I have performed InterProScan analysis of this sequence to know information related to Domains, active site and family of protein to which protein sequence belongs.