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Eukaryotic chromosomes are linear. What would happen to a chromosome in these situations? When during the...

Eukaryotic chromosomes are linear. What would happen to a chromosome in these situations? When during the cell cycle would these problems arise if it..?

a. Lost all of its origins of replication?

b. lost all of the DNA constituting the centromere?

c. Lost one of its telomeres?

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Answer #1

Eukaryotic chromosomes are linear in which chromosome consists enormously long linear DNA molecule associated with protiens that fold and pack the fine thread of DNA into a more compact structure. Chromosomes contain long strands of DNA containing genetic information.

a. During the cell cycle, if all of the origins of replication are lost then no replication will occur during S-phase and replication would not start.

b. In case of lost of all the DNA constituting the centromere, it would not be possible to have sister chromatids and therefore they could not be pulled apart in anaphase making one of the cells DNA- less.

c. To prevent the loss of essential genetic information during replication, the ends of DNA in chromosomes contains special structures called telomeres. So, due to the loss of one of its telomeres, it would shorten the DNA and genetic information would be lost.

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