Example of DNA synthesis or repair:-
E .coli that has only 4600000 base pair but complete the process of replication within 18 minutes that means the average rate of polymerization has to be approximately 2,000 base pair per second
Not only do this polymerase have to be fast but they also have to catalyse the reaction with high degree of accuracy any mistake during replication would result into mutations
Furthermore energetically replication is a very expensive process .
Deoxyribonucleoside triphosphate serve as dual purpose in addition to acting as substrate they provide energy for polymerization reaction this to Terminal phosphate in the deoxynucleoside triphosphate are high energy phosphate same as in case of ATP.
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